Article

<sup>UFM</sup> Track: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

2023-01-06

Abstract excerpt

The endothelial blood-brain barrier (BBB) strictly controls immune cell trafficking into the central nervous system (CNS). In neuroinflammatory diseases such as multiple sclerosis, this tight control is, however, disturbed, leading to immune cell infiltration into the CNS. The development of in vitro models of the BBB combined with microfluidic devices has advanced our understanding of the cellular and molecular m...

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Literature Corpus work: 5134faac-db9f-5a2a-b9fd-cb9c1c8d2e7f
DOI: 10.1101/2023.01.04.522827

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