Article
Disruption of histidine catabolism in NEUT2 mice.
Archives of biochemistry and biophysics - 15 Aug 2001
Cook R J
Abstract excerpt
Homozygous NEUT2 mice lack cytosolic 10-formyltetrahydrofolate dehydrogenase (FDH; Champion et al. (1994) Proc. Natl. Acad. Sci. USA 91, 11,338-11,342) and as a consequence should be unable to oxidize carbon 2 of l-histidine to CO2 via 10-formyltetrahydrofolate in liver cytosol. There was essenti...
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