Article
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.
Gastroenterology - 1 Nov 2006
Spring Kevin J, Zhao Zhen Zhen, Karamatic Rozemary, Walsh Michael D, Whitehall Vicki L J, Pike Tanya, Simms Lisa A, Young Joanne, James Michael, Montgomery Grant W, Appleyard Mark, Hewett David, Togashi Kazutomo, Jass Jeremy R, Leggett Barbara A
Abstract excerpt
BACKGROUND & AIMS: Sporadic colorectal cancers with a high degree of microsatellite instability are a clinically distinct subgroup with a high incidence of BRAF mutation and are widely considered to develop from serrated polyps. Previous studies of serrated polyps have been highly selected and largely retrospective. This prospective study examined the prevalence of sessile serrated adenomas and determined the...
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