Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Central and peripheral dysregulation of melanin-concentrating hormone in obese Zucker rats.

Brain research. Molecular brain research - 15 Aug 2001

Stricker-Krongrad A, Dimitrov T, Beck B

Abstract excerpt

Melanin concentrating hormone (MCH) is a peptide synthesized in the lateral hypothalamus which stimulates food ingestion and leptin secretion in rodents. In this experiment, we measured the expressions of MCH as well as of its receptor (SLC-1) in the hypothalamus of obese hyperphagic and lean Zucker rats by quantitative real time RT-PCR. MCH mRNA expression in the obese rats was significantly increased by a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Leptin
Share to Melanins
Share to Obesity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Pituitary Hormones

Share to Protein Precursors

Share to Rats, Zucker

Share to Receptors, Cell Surface

Share to Receptors, Leptin

Source

Identifiers

PMID: 11483240
DOI: 10.1016/s0169-328x(01)00130-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Central and peripheral dysregulation of melanin-concentrating hormone in obese Zucker rats.PMID 11483240Read ↗

Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity.Semantic proximity Read ↗

Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.Semantic proximity Read ↗

Expression of Melanin-Concentrating Hormone Receptor 2 Protects Against Diet-Induced Obesity in Male MiceSemantic proximity Read ↗

The melanocortin-4 receptor as target for obesity treatment: a systematic review of emerging pharmacological therapeutic options.Semantic proximity Read ↗

Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats.Semantic proximity Read ↗

Meta-analysis of melanin-concentrating hormone signaling-deficient mice on behavioral and metabolic phenotypes.Semantic proximity Read ↗

Neuropeptides and obesity.Semantic proximity Read ↗

Leptin and melanocortin signaling in the hypothalamus.Semantic proximity Read ↗

The central melanocortin system and the regulation of energy balance.Semantic proximity Read ↗

Pro-opiomelanocortin (POMC) Deficiency and Peripheral Melanocortins in ObesitySemantic proximity Read ↗

Hypothalamic expression of urocortin 3 and the type 2 corticotropin-releasing factor receptor is regulated according to feeding state in lean but not obese Zucker rats.Semantic proximity Read ↗

Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.