Article
Germline structure and differential utilization of Igha and Ighb VH10 genes.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1999
Whitcomb E A, Haines B B, Parmelee A P, Pearlman A M, Brodeur P H
Abstract excerpt
Ab heavy chains encoded by mouse VH10 genes have been of particular interest due to their frequent association with DNA binding. We reported previously that VH10 sequences are over-represented in the preimmune repertoire considering the apparent number of germline-encoded VH10 gene segments. In this report, we show that the VH10 family consists of three and two germline genes in the Igha and Ighb haplotypes,...
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