Germline structure and differential utilization of Igha and Ighb VH10 genes.

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Article

Germline structure and differential utilization of Igha and Ighb VH10 genes.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1999

Whitcomb E A, Haines B B, Parmelee A P, Pearlman A M, Brodeur P H

Abstract excerpt

Ab heavy chains encoded by mouse VH10 genes have been of particular interest due to their frequent association with DNA binding. We reported previously that VH10 sequences are over-represented in the preimmune repertoire considering the apparent number of germline-encoded VH10 gene segments. In t...

Topics

Alleles
Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antibody Diversity
Antibody Specificity
Antigens
B-Lymphocytes
Base Sequence
Cloning, Molecular
DNA
DNA Probes
DNA, Complementary
Gene Rearrangement, B-Lymphocyte
Genes, Immunoglobulin
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Mice

Source

Open in PubMed

Identifiers

PMID: 9973411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9973411-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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