Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polarization of T-helper lymphocytes toward the Th2 phenotype in uremic patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 2001

Libetta C, Rampino T, Dal Canton A

Abstract excerpt

T-helper (Th) lymphocytes consist of Th1 and Th2 subsets. Th1 cells are effectors of cell-mediated immunity and secrete interferon-gamma (IFN-gamma), which recruits new Th1 cells in cooperation with interleukin-12 (IL-12; produced by monocytes) and inhibits Th2 differentiation. Th2 cells produce IL-4 and IL-10, which inhibit IFN-gamma secretion and cell immunity. We investigated whether the impaired immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunity, Cellular
Share to Interleukin-10
Share to Interleukin-4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kidney Failure, Chronic

Share to Leukocytes, Mononuclear

Share to Renal Dialysis

Share to Th1 Cells

Share to Th2 Cells

Source

Identifiers

PMID: 11479154
DOI: 10.1053/ajkd.2001.26092

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polarization of T-helper lymphocytes toward the Th2 phenotype in uremic patients.PMID 11479154Read ↗

Reduced capacity of mononuclear cells to synthesize cytokines against an inflammatory stimulus in uremic patients.Semantic proximity Read ↗

Impairment of innate cellular response to in vitro stimuli in patients on continuous ambulatory peritoneal dialysis.Semantic proximity Read ↗

Monocytes in Uremia.Semantic proximity Read ↗

M2 monocyte polarization in dialyzed patients is associated with increased levels of M-CSF and myeloperoxidase-associated oxidative stress: preliminary resultsSemantic proximity Read ↗

The imbalance in the ratio of Th1 and Th2 helper lymphocytes in uraemia is mediated by an increased apoptosis of Th1 subsetSemantic proximity Read ↗

T-cell function, T-cell phenotype and its role in responsiveness to recombinant human erythropoietin in hemodialysis patients.Semantic proximity Read ↗

Altered Monocytic Phenotypes are Associated with Uraemic Pruritus in Patients Receiving Haemodialysis.Semantic proximity Read ↗

Immune deficiency in uremia: interleukin-2 production and responsiveness and interleukin-2 receptor expression and release.Semantic proximity Read ↗

CCR5Δ32 genotype leads to a Th2 type directed immune response in ESRD patients.Semantic proximity Read ↗

Hemodiafiltration May Be Associated with Senescence-Related Phenotypic Alterations of Lymphocytes, Which May Predict Mortality in Patients Undergoing Dialysis.Semantic proximity Read ↗

Shift toward T lymphocytes with a T helper 1 cytokine-secretion profile in the joints of patients with rheumatoid arthritis.Semantic proximity Read ↗

Ribavirin upregulates interleukin-12 receptor and induces T cell differentiation towards type 1 in chronic hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.