Article
Impairment of innate cellular response to in vitro stimuli in patients on continuous ambulatory peritoneal dialysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2005
Ando Minoru, Shibuya Asuka, Yasuda Masako, Azuma Naoko, Tsuchiya Ken, Akiba Takashi, Nitta Kousaku
Abstract excerpt
BACKGROUND: Most crucial in the initial stages of host defence against invading micro-organisms is innate immunity, in which peripheral mononuclear cells, in particular cytokines, are pivotal. Mortality from infections is high in dialysis patients, but it remains unclear if this arises from the ineffectiveness of innate immune mechanisms. METHODS: In 20 haemodialysis (HD) patients, 20 patients on continuous...
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