Article
Immune deficiency in uremia: interleukin-2 production and responsiveness and interleukin-2 receptor expression and release.
Nephron - 1 Jan 1991
Donati D, Degiannis D, Homer L, Gastaldi L, Raskova J, Raska K
Abstract excerpt
We have studied the role of interleukin-2 (IL-2) and its receptors in the impaired in vitro lymphocyte response characteristic of hemodialysis patients treated by means of cuprophane membranes. The proliferative response of T lymphocytes as well as T-cell-dependent B cell proliferation after stimulation with mitogens was significantly reduced in hemodialysis patients. The in vitro production of IL-2 after such...
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