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Article

Immune deficiency in uremia: interleukin-2 production and responsiveness and interleukin-2 receptor expression and release.

Nephron - 1 Jan 1991

Donati D, Degiannis D, Homer L, Gastaldi L, Raskova J, Raska K

Abstract excerpt

We have studied the role of interleukin-2 (IL-2) and its receptors in the impaired in vitro lymphocyte response characteristic of hemodialysis patients treated by means of cuprophane membranes. The proliferative response of T lymphocytes as well as T-cell-dependent B cell proliferation after stim...

Topics

Aged
Cell Count
Cell Division
Cells, Cultured
Down-Regulation
Female
Humans
Immunologic Deficiency Syndromes
Interleukin-2
Lectins
Lymphocytes
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mitogens

Phenotype

Receptors, Interleukin-2

Recombinant Proteins

Renal Dialysis

Source

Identifiers

PMID: 1896091
DOI: 10.1159/000186435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1896091-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Immune deficiency in uremia: interleukin-2 production and responsiveness and interleukin-2 receptor expression and release.PMID 1896091Read ↗

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Reduced capacity of mononuclear cells to synthesize cytokines against an inflammatory stimulus in uremic patients.Semantic proximity Read ↗

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