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Article

Reduced capacity of mononuclear cells to synthesize cytokines against an inflammatory stimulus in uremic patients.

Nephron. Clinical practice - 1 Jan 2006

Ando Minoru, Shibuya Asuka, Tsuchiya Ken, Akiba Takashi, Nitta Kosaku

Abstract excerpt

BACKGROUND: The local production of cytokines and phagocytosis is pivotal in innate immunity. Uremic patients have a high infectious morbidity, but it remains unclear if this arises from incompetence of these local cellular functions. METHODS: In 30 predialysis uremic patients and 20 controls, we studied the intracellular cytokine synthesis by mononuclear cells in response to stimulation. Moreover, phagocytic...

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Identifiers

PMID: 16837784
DOI: 10.1159/000094446

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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