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Article

Genetic variation in physiological sensitivity to estrogen in mice.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 May 2001

Spearow J L, O'Henley P, Doemeny P, Sera R, Leffler R, Sofos T, Barkley M

Abstract excerpt

Genetic variation in susceptibility to endocrine disruption by estrogenic agents was examined in juvenile male mice. Mice were implanted with increasing doses of estradiol (E2) at 3 weeks of age and reproductive responses were determined 3 weeks later. Greater than 16-fold differences in susceptibility to the disruption of reproductive development by E2 were detected between strains of mice. CD-1 was much more...

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Identifiers

PMID: 11478683
DOI: 10.1034/j.1600-0463.2001.090504.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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