Article
Reassessment of models used to test xenobiotics for oestrogenic potency is overdue.
Human reproduction (Oxford, England) - 1 May 2001
Spearow J L, Barkley M
Abstract excerpt
Product safety bioassays need to include data from animals with susceptible genotypes or the potential for environmental compounds to disrupt reproductive development in hormonally sensitive populations may be greatly underestimated. The continued use of resistant animal models is likely to result in allowable releases of toxic levels of oestrogenic agents that could differentially disrupt reproductive...
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