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Article

DJ-1 Positively Regulates the Androgen Receptor by Impairing the Binding of PIASxα to the Receptor

1 Oct 2001

Abstract excerpt

DJ-1 was first identified as a novel candidate of the oncogene product that transformed mouse NIH3T3 cells in cooperation with an activated ras. Later DJ-1 was also found to be an infertility-related protein that was reduced in rat sperm treated with sperm toxicants that cause infertility in rats. To determine the functions of DJ-1, cDNAs encoding DJ-1-binding proteins were screened by the yeast two-hybrid...

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PMID: 11477070
DOI: 10.1074/jbc.m101730200

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