Article
Transcriptional interferences between normal or mutant androgen receptors and the activator protein 1--dissection of the androgen receptor functional domains.
Endocrinology - 1 Jan 1999
Lobaccaro J M, Poujol N, Térouanne B, Georget V, Fabre S, Lumbroso S, Sultan C
Abstract excerpt
We investigated the interferences of the normal or mutated androgen receptor with the activator protein-1 (AP-1) by assessing their effects on transcriptional activity in CV-1 cells. A luciferase reporter gene was constructed downstream from either a promoter for the mouse vas deferens protein, o...
Topics
- Aldehyde Reductase
- Androgens
- Animals
- Breast Neoplasms, Male
- COS Cells
- DNA
- Enzyme Inhibitors
- Genes, Reporter
- Genetic Engineering
- Humans
- Luciferases
- Male
- Marine Toxins
- Mice
- Mutation
- Okadaic Acid
- Oxazoles
- Proteins