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Article

Receptor for Activated C Kinase 1 (RACK1) and Src Regulate the Tyrosine Phosphorylation and Function of the Androgen Receptor

15 Nov 2006

Abstract excerpt

The androgen receptor (AR) remains functionally important in the development and progression of prostate cancer even when the disease seems androgen "independent." Because signal transduction by growth factor receptors increases in advanced prostate cancer and is capable of sensitizing the AR to androgen, there is considerable interest in determining the mechanisms by which signaling systems can modulate AR...

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Share to Estrogen and related hormone effects
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Identifiers

PMID: 17108144
DOI: 10.1158/0008-5472.can-06-0596

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