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Functional characterization of E- and P-cadherin in invasive breast cancer cells

3 Mar 2009

Abstract excerpt

BACKGROUND: Alterations in the cadherin-catenin adhesion complexes are involved in tumor initiation, progression and metastasis. However, the functional implication of distinct cadherin types in breast cancer biology is still poorly understood. METHODS: To compare the functional role of E-cadherin and P-cadherin in invasive breast cancer, we stably transfected these molecules into the MDA-MB-231 cell line, and...

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PMID: 19257890
DOI: 10.1186/1471-2407-9-74

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