Article
[Pharmacogenetics: pharmacokinetics and clinical implications].
Recenti progressi in medicina - 1 Jan 1997
Blardi P
Abstract excerpt
In the last years, pharmacogenetic studies tried to identify the hereditary bases characterizing different individual response to drugs. Human organism tries to remove drugs by activating enzyme systems. Metabolization reaction rate shows wide interindividual variations, being characterized by different factors, such as physiologic (age, sex), pathologic (liver and kidney diseases), and genetic characteristics....
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