Article
Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer.
The Journal of clinical investigation - 15 Sept 1997
Churchill P C, Churchill M C, Bidani A K, Griffin K A, Picken M, Pravenec M, Kren V, St Lezin E, Wang J M, Wang N, Kurtz T W
Abstract excerpt
To test the hypothesis that genetic factors can determine susceptibility to hypertension-induced renal damage, we derived an experimental animal model in which two genetically different yet histocompatible kidneys are chronically and simultaneously exposed to the same blood pressure profile and m...
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