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Article

Rapid evolution of novel traits in microorganisms.

Applied and environmental microbiology - 1 Aug 2001

Selifonova O, Valle F, Schellenberger V

Abstract excerpt

The use of natural microorganisms in biotransformations is frequently constrained by their limited tolerance to the high concentrations of metabolites and solvents required for effective industrial production. In many cases, more robust strains have to be generated by random mutagenesis and selection. This process of directed evolution can be accelerated in mutator strains, which carry defects in one or more of...

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Identifiers

PMID: 11472942
DOI: 10.1128/AEM.67.8.3645-3649.2001
PMCID: PMC93066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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