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Article

Differences in the expression of human class I MHC alleles and their associated peptides in the presence of proteasome inhibitors.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2001

Luckey C J, Marto J A, Partridge M, Hall E, White F M, Lippolis J D, Shabanowitz J, Hunt D F, Engelhard V H

Abstract excerpt

We have studied the contributions of proteasome inhibitor-sensitive and -insensitive proteases to the generation of class I MHC-associated peptides. The cell surface expression of 13 different human class I MHC alleles was inhibited by as much as 90% or as little as 40% when cells were incubated with saturating concentrations of three different proteasome inhibitors. Inhibitor-resistant class I MHC expression was...

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Source

Identifiers

PMID: 11466336
DOI: 10.4049/jimmunol.167.3.1212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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