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Article

The MHC class I peptide repertoire is molded by the transcriptome.

The Journal of experimental medicine - 17 Mar 2008

Fortier Marie-Hélène, Caron Etienne, Hardy Marie-Pierre, Voisin Grégory, Lemieux Sébastien, Perreault Claude, Thibault Pierre

Abstract excerpt

Under steady-state conditions, major histocompatibility complex (MHC) I molecules are associated with self-peptides that are collectively referred to as the MHC class I peptide (MIP) repertoire. Very little is known about the genesis and molecular composition of the MIP repertoire. We developed a novel high-throughput mass spectrometry approach that yields an accurate definition of the nature and relative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18299400
DOI: 10.1084/jem.20071985
PMCID: PMC2275383

Genes

MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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