Article

Phospholipase C Zeta in Human Spermatozoa: A Systematic Review on Current Development and Clinical Application

2023-12-26

Abstract excerpt

During fertilization, the fusion of the spermatozoa with the oocytes causes the release of calcium from the oocyte endoplasmatic reticulum. This, in turn, triggers a series of calcium ion (Ca2+) oscillations, a process known as oocyte activation. The sperm-specific factor responsible for oocyte activation is phospholipase C zeta (PLCζ). Men undergoing intracytoplasmic sperm injection (ICSI) with their spermatozoa...

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Literature Corpus work: 4d19dfd4-60a9-5718-80f6-53684661e973
DOI: 10.20944/preprints202312.1738.v1

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