Two sources of genetic liability to depression: interpreting the relationship between stress sensitivity and depression under a multifactorial polygenic model.

Abstract excerpt

Psychopathology theories, clinical observations, and research all point to multiple sources of liability to depression. This article uses a longitudinal twin-study design to characterize the contribution of two genetically-influenced sources of depression risk: the first corresponding to stress sensitivity and the second representing risk that is independent of stress sensitivity. The sample consisted of 606...

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