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Article

Male reproductive phenotypes in double mutant mice lacking both FSHbeta and activin receptor IIA.

Endocrinology - 1 Aug 2001

Kumar T R, Varani S, Wreford N G, Telfer N M, de Kretser D M, Matzuk M M

Abstract excerpt

Activins are known to signal through two serine/threonine kinase type II receptors. Activin receptor IIA is widely expressed in the male reproductive axis, including the pituitary and testis. Our previous studies using gene knockout mice have confirmed the essential in vivo role of activin receptor IIA in FSH homeostasis. Activin receptor IIA-null male mice are fertile, have suppressed pituitary and serum FSH...

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Source

Identifiers

PMID: 11459797
DOI: 10.1210/endo.142.8.8336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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