Article
The role of follicle-stimulating hormone in spermatogenesis: lessons from knockout animal models.
Archives of medical research - 1 Jan 2000
Sairam M R, Krishnamurthy H
Abstract excerpt
The development of knockout mouse models for the FSH-beta subunit, the FSH receptor, and LH-receptor performed in different laboratories has confirmed and extended our knowledge concerning the critical role of these hormone-signaling systems in spermatogenesis. In this article, we summarize the phenotypic changes observed in male FSH receptor knockout (FORKO) mice. Young FORKO males have underdeveloped testis...
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