Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional analysis of LHbeta knockout mice.

Molecular and cellular endocrinology - 15 Apr 2007

Kumar T Rajendra

Abstract excerpt

LH and FSH act on gonadal cells to regulate steroidogenesis and gametogenesis. To model human reproductive disorders involving loss of LH function and to define LH-responsive genes, we produced knockout mice lacking the hormone-specific LHbeta subunit. LHbeta null mice are viable but demonstrate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chorionic Gonadotropin
Share to Gene Targeting
Share to Gonads

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Phenotype

Source

Identifiers

PMID: 17350160
DOI: 10.1016/j.mce.2006.10.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17350160-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional analysis of LHbeta knockout mice.PMID 17350160Read ↗

What have we learned about gonadotropin function from gonadotropin subunit and receptor knockout mice?Semantic proximity Read ↗

Mutations of follicle stimulating hormone-beta and its receptor in human and mouse: genotype/phenotype.Semantic proximity Read ↗

Mutations in the follicle-stimulating hormone-beta (FSH beta) and FSH receptor genes in mice and humans.Semantic proximity Read ↗

The role of follicle-stimulating hormone in spermatogenesis: lessons from knockout animal models.Semantic proximity Read ↗

Male reproductive phenotypes in double mutant mice lacking both FSHbeta and activin receptor IIA.Semantic proximity Read ↗

Targeted gene disruption in zebrafish reveals noncanonical functions of LH signaling in reproduction.Semantic proximity Read ↗

Inactivating mutations of luteinizing hormone beta-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women.Semantic proximity Read ↗

The Luteinizing Hormone Receptor Knockout Mouse as a Tool to Probe the In Vivo Actions of Gonadotropic Hormones/Receptors in Females.Semantic proximity Read ↗

Oestrogen receptor knockout mice: roles for oestrogen receptors alpha and beta in reproductive tissues.Semantic proximity Read ↗

Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice.Semantic proximity Read ↗

Gonadotropin Signaling in Zebrafish Ovary and Testis Development: Insights From Gene Knockout StudySemantic proximity Read ↗

The molecular basis of impaired follicle-stimulating hormone action: evidence from human mutations and mouse models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.