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Article

Functional analysis of LHbeta knockout mice.

Molecular and cellular endocrinology - 15 Apr 2007

Kumar T Rajendra

Abstract excerpt

LH and FSH act on gonadal cells to regulate steroidogenesis and gametogenesis. To model human reproductive disorders involving loss of LH function and to define LH-responsive genes, we produced knockout mice lacking the hormone-specific LHbeta subunit. LHbeta null mice are viable but demonstrate postnatal defects in gonadal growth and function resulting in infertility. Mutant males have decreased testes size, a...

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PMID: 17350160
DOI: 10.1016/j.mce.2006.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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