Article
Threshold-specific requirements for Bmp4 in mandibular development.
Developmental biology - 15 Jul 2005
Liu Wei, Selever Jennifer, Murali Deepa, Sun Xiaoxia, Brugger Sean M, Ma Lijiang, Schwartz Robert J, Maxson Robert, Furuta Yasuhide, Martin James F
Abstract excerpt
Mandibular development is regulated by an interplay between a specified branchial arch ectoderm and a plastic mesenchyme. Moreover, signaling from the pharyngeal endoderm has been shown to be important for mandibular morphogenesis. To gain insight into the mechanisms regulating mandibular pattern, it is important to investigate the function of the epithelial-derived signals. Bmp4 is expressed in both distal,...
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