Characterization of the SarA virulence gene regulator of <i>Staphylococcus aureus</i>

doi:10.1046/j.1365-2958.1999.01474.x

Article

Characterization of the SarA virulence gene regulator of <i>Staphylococcus aureus</i>

1 Jul 1999

Abstract excerpt

Staphylococcus aureus is a potent human pathogen that expresses a large number of virulence factors in a temporally regulated fashion. Two pleiotropically acting regulatory loci were identified in previous mutational studies. The agr locus comprises two operons that express a quorum-sensing system from the P2 promoter and a regulatory RNA molecule from the P3 promoter. The sar locus encodes a DNA-binding protein...

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