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Article

Characterization of Virulence Factor Regulation by SrrAB, a Two-Component System in <i>Staphylococcus aureus</i>

2 Apr 2004

Abstract excerpt

Workers in our laboratory have previously identified the staphylococcal respiratory response AB (SrrAB), a Staphylococcus aureus two-component system that acts in the global regulation of virulence factors. This system down-regulates production of agr RNAIII, protein A, and toxic shock syndrome toxin 1 (TSST-1), particularly under low-oxygen conditions. In this study we investigated the localization and membrane...

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Identifiers

PMID: 15060046
DOI: 10.1128/jb.186.8.2430-2438.2004

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