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Article

Hepatitis B virus and hepatocellular carcinoma.

1 Apr 2001

Abstract excerpt

Chronic hepatitis B virus (HBV) infection is a major global cause of hepatocellular carcinoma (HCC). Individuals who are chronic carriers have a greater than 100-fold increased relative risk of developing the tumour. Several mechanisms of HBV-induced HCC have been proposed. Integration of HBV DNA into the genome of hepatocytes occurs commonly, although integration at cellular sites that are important for...

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Identifiers

PMID: 11454100
DOI: 10.1111/j.1365-2613.2001.iep0082-0077-x

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