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Article

Hepatocellular carcinoma and hepatitis B virus.

Seminars in liver disease - 1 May 2006

Chan Henry Lik-Yuen, Sung Joseph Jao-Yiu

Abstract excerpt

Chronic hepatitis B is the most common cause of hepatocellular carcinoma (HCC) in Asia. Integration of hepatitis B virus (HBV) genome is likely an early event of carcinogenesis. The integrated HBV genome may activate neighboring cellular genes directly to offer a selective growth advantage to the liver cells. Production of hepatitis B X protein can act as a transactivator on various cellular genes for tumor...

Topics

Carcinoma, Hepatocellular
DNA, Viral
Disease Progression
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Neoplasms
Mutation
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16673293
DOI: 10.1055/s-2006-939753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16673293-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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