Article
Susceptibility to cerulein-induced pancreatitis in inducible nitric oxide synthase-deficient mice.
Pancreas - 1 Jul 2001
Qui B, Mei Q B, Ma J J, Korsten M A
Abstract excerpt
Production of nitric oxide (NO) by inducible nitric oxide synthase (iNOS) has been proposed as a pathogenic factor in acute pancreatitis, but its role has still not been fully examined. The present study explored the role of iNOS in cerulein-induced acute pancreatitis using iNOS-deficient mice. Twelve- to 14-week-old male mice (C57B1/6 and iNOS-deficient) were administered cerulein by intraperitoneal (i.p.)...
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