Article
Role of copper,zinc-superoxide dismutase in catalyzing nitrotyrosine formation in murine liver.
Free radical biology & medicine - 1 Sept 2008
Zhu Jian-Hong, Zhang Xiaomei, Roneker Carol A, McClung James P, Zhang Sheng, Thannhauser Theodore W, Ripoll Daniel R, Sun Qi, Lei Xin Gen
Abstract excerpt
The only known function of Cu,Zn-superoxide dismutase (SOD1) is to catalyze the dismutation of superoxide anion into hydrogen peroxide. Our objective was to determine if SOD1 catalyzes murine liver protein nitration induced by acetaminophen (APAP) and lipopolysaccharide (LPS). Liver and plasma sa...
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