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Article

Urinary tract infection in iNOS-deficient mice with focus on bacterial sensitivity to nitric oxide.

American journal of physiology. Renal physiology - 1 Jan 2003

Poljakovic Mirjana, Persson Katarina

Abstract excerpt

Inducible nitric oxide synthase (iNOS)-deficient mice were used to examine the role of iNOS in Escherichia coli-induced urinary tract infection (UTI). The toxicity of nitric oxide (NO)/peroxynitrite to bacteria and host was also investigated. The nitrite levels in urine of iNOS+/+ but not iNOS/ mice increased after infection. No differences in bacterial clearance or persistence were noted between the genotypes....

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Source

Identifiers

PMID: 12494944
DOI: 10.1152/ajprenal.00101.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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