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Article

Modelling Alzheimer's disease in multiple transgenic mice.

Biochemical Society symposium - 1 Jan 2001

Dewachter I, Moechars D, van Dorpe J, Tesseur I, Van den Haute C, Spittaels K, Van Leuven F

Abstract excerpt

We have reported transgenic mice with neuronal overexpression of the clinical mutant beta-amyloid precursor protein (APP) known as London, which develop an AD-related phenotype [Moechers, Dewachter, Lorent, Reversé, Baekelandt, Nadiu, Tesseur, Spittaels, Van den Haute, Checler, et al. (1999) J. Biol. Chem. 274, 6483-6492]. Characterized early symptoms (3-9 months) include disturbed behaviour, neophobia,...

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Identifiers

PMID: 11447836
DOI: 10.1042/bss0670203

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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