Article
Further evidence for a bipolar risk gene on chromosome 12q24 suggested by investigation of haplotype sharing and allelic association in patients from the Faroe Islands.
Molecular psychiatry - 1 Jul 2001
Degn B, Lundorf M D, Wang A, Vang M, Mors O, Kruse T A, Ewald H
Abstract excerpt
A number of studies have strongly suggested a susceptibility locus for bipolar affective disorder on chromosome 12q24. The present study investigates for a shared chromosomal segment among distantly related patients with bipolar affective disorder from the Faroe Islands, using 17 microsatellite markers covering 24 cM in the previously suggested region on chromosome 12q24. D12S342 showed possible allelic...
Topics
- Bipolar Disorder
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- DNA
- Denmark
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Male
- Microsatellite Repeats
- Pedigree
- Risk Factors