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Article

Significant linkage between bipolar affective disorder and chromosome 12q24.

Psychiatric genetics - 1 Jan 1998

Ewald H, Degn B, Mors O, Kruse T A

Abstract excerpt

Chromosome 12q23-q24.1 has been implied by a few linkage and association studies as a candidate region for affective disorder. The present study investigated for linkage between bipolar affective disorder and 16 microsatellite markers covering chromosome 12q22-q24 in two Danish families. Assuming homogeneity and a dominant mode of inheritance, a significant two-point lod score of 3.37 was found at D12S1639, when...

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Identifiers

PMID: 9800214
DOI: 10.1097/00041444-199800830-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Significant linkage between bipolar affective disorder and chromosome 12q24.PMID 9800214Read ↗

Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q.Semantic proximity Read ↗

Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.Semantic proximity Read ↗

A genome-wide scan points to a susceptibility locus for bipolar disorder on chromosome 12.Semantic proximity Read ↗

A possible susceptibility locus for bipolar affective disorder in chromosomal region 10q25--q26.Semantic proximity Read ↗

Candidate region linkage analysis in twins discordant or concordant for depression symptomatology.Semantic proximity Read ↗

Further evidence for a bipolar risk gene on chromosome 12q24 suggested by investigation of haplotype sharing and allelic association in patients from the Faroe Islands.Semantic proximity Read ↗

Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.Semantic proximity Read ↗

A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19.Semantic proximity Read ↗

A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus.Semantic proximity Read ↗

A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q.Semantic proximity Read ↗

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