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Article

SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor.

Molecular microbiology - 1 Jun 2001

Slomińska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G

Abstract excerpt

The SeqA protein is a negative regulator of initiation of DNA replication in the Escherichia coli chromosome. Here, we demonstrate that SeqA stimulates transcription from the bacteriophage lambda pR promoter both in vivo and in vitro. The activity of the lambda pL promoter was found not to be affected by this protein. SeqA-mediated stimulation of pR was dependent on the state of template methylation:...

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Share to Bacterial Outer Membrane Proteins
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Identifiers

PMID: 11442835
DOI: 10.1046/j.1365-2958.2001.02480.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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