Article
SeqA-mediated stimulation of a promoter activity by facilitating functions of a transcription activator.
Molecular microbiology - 1 Mar 2003
Słomińska Monika, Konopa Grazyna, Ostrowska Justyna, Kedzierska Barbara, Wegrzyn Grzegorz, Wegrzyn Alicja
Abstract excerpt
It was demonstrated recently that the SeqA protein, a main negative regulator of Escherichia coli chromosome replication initiation, is also a specific transcription factor. SeqA specifically activates the bacteriophage lambda pR promoter while revealing no significant effect on the activity of another lambda promoter, pL. Here, we demonstrate that lysogenization by bacteriophage lambda is impaired in E. coli...
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