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Article

Pathogenic effects of D23N Iowa mutant amyloid beta -protein.

The Journal of biological chemistry - 31 Aug 2001

Van Nostrand W E, Melchor J P, Cho H S, Greenberg S M, Rebeck G W

Abstract excerpt

Cerebral amyloid beta-protein angiopathy (CAA) is a key pathological feature of patients with Alzheimer's disease and certain related disorders. In these conditions the CAA is characterized by the deposition of Abeta within the cerebral vessel wall and, in severe cases, hemorrhagic stroke. Several mutations have been identified within the Abeta region of the Abeta protein precursor (AbetaPP) gene that appear to...

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Identifiers

PMID: 11441013
DOI: 10.1074/jbc.M104135200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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