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Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor.

Annals of the New York Academy of Sciences - 1 Nov 2002

Van Nostrand William E, Melchor Jerry P, Romanov Galina, Zeigler Kelly, Davis Judianne

Abstract excerpt

Cerebral amyloid beta-protein angiopathy (CAA) is a key pathological feature of patients with Alzheimer's disease and certain related disorders. Several mutations have been identified within the Abeta region of the Abeta protein precursor (AbetaPP) gene that appear to enhance the severity of CAA....

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Identifiers

PMID: 12480759
DOI: 10.1111/j.1749-6632.2002.tb04824.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12480759-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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