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Article

Abeta species, including IsoAsp23 Abeta, in Iowa-type familial cerebral amyloid angiopathy.

Acta neuropathologica - 1 Mar 2003

Shin Youngah, Cho Hyun Soon, Fukumoto Hiroaki, Shimizu Takahiko, Shirasawa Takuji, Greenberg Steven M, Rebeck G William

Abstract excerpt

Mutations within the Abeta sequence of the AbetaPP gene are associated with familial forms of cerebral amyloid angiopathy (CAA). One mutation, Abeta D23N, was identified in a family in Iowa with a clinical history of early-onset dementia. We analyzed the pattern of Abeta deposition in the hippocampus of an individual with Iowa CAA. In addition to strong amyloid angiopathy, we found unusual diffuse Abeta deposits...

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Identifiers

PMID: 12557012
DOI: 10.1007/s00401-002-0639-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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