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Article

Expression of ??-synuclein in a human glioma cell line and its up-regulation by interleukin-1??

1 Jul 2001

Abstract excerpt

Although alpha-synuclein is expressed primarily in neurons, it is a major component of oligodendroglial and astrocytic inclusions in several neurodegenerative diseases. Recent study has further demonstrated that alpha-synuclein is expressed in cultured rat oligodendrocytes. We determined whether alpha-synuclein might be expressed in astrocytic cells. alpha-Synuclein mRNA and protein were detected in U251 human...

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PMID: 11435921
DOI: 10.1097/00001756-200107030-00028

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