Article
Linking class-switch recombination with somatic hypermutation.
Nature reviews. Molecular cell biology - 1 Jul 2001
Kinoshita K, Honjo T
Abstract excerpt
The recent discovery of a molecular link between two apparently different genetic alteration events--class-switch recombination and somatic hypermutation--has led to the idea that the recognition and cleavage of target DNA in these two events might be mediated by similar or identical molecules to those involved in RNA editing. This could mean that the complexity of mammalian genetic information may be enriched by...
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