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Article

The effect of the beta(2) adrenoceptor gene Thr164Ile polymorphism on human adipose tissue lipolytic function.

British journal of pharmacology - 1 Jul 2001

Hoffstedt J, Iliadou A, Pedersen N L, Schalling M, Arner P

Abstract excerpt

A rare beta(2)-adrenoceptor gene polymorphism, Thr164Ile, has been described that impairs receptor function when transfected into cell lines. We investigated whether the polymorphism influences native receptor function by studying lipolysis in freshly isolated subcutaneous fat cells from 236 apparently healthy subjects. Twelve subjects were heterozygous for the 164Ile variant. The fat cells of Ile carriers...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Dose-Response Relationship, Drug

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Share to Receptors, Adrenergic, beta-2

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Identifiers

PMID: 11429395
DOI: 10.1038/sj.bjp.0704125
PMCID: PMC1572833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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