Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.

Chest - 1 Feb 1999

Lipworth B J, Hall I P, Tan S, Aziz I, Coutie W

Abstract excerpt

BACKGROUND: Genetic polymorphism determines agonist-induced down-regulation and desensitization of beta2-adrenoceptors. OBJECTIVES: The aim of the present study was to investigate the effects of genetic polymorphism on ex vivo (lymphocytes) and in vivo (bronchoprotection) function of beta2-adreno...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Adrenergic beta-Agonists
Share to Asthma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bronchial Provocation Tests

Share to Ethanolamines

Share to Lymphocytes

Share to Receptors, Adrenergic, beta-2

Share to Spirometry

Source

Identifiers

PMID: 10027427
DOI: 10.1378/chest.115.2.324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10027427-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.PMID 10027427Read ↗

Polymorphism of the beta2-adrenoceptor and the response to long-term beta2-agonist therapy in asthma.Semantic proximity Read ↗

Influence of genetic polymorphisms in the beta2-adrenoceptor on desensitization in human lung mast cells.Semantic proximity Read ↗

Pharmacogenetics of β2 adrenergic receptor gene polymorphisms, long-acting β-agonists and asthmaSemantic proximity Read ↗

Influence of beta 2-adrenergic receptor genotypes on signal transduction in human airway smooth muscle cells.Semantic proximity Read ↗

Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial.Semantic proximity Read ↗

Polymorphism of the beta(2)-adrenergic receptor gene and desensitization in human airway smooth muscle.Semantic proximity Read ↗

Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism.Semantic proximity Read ↗

Differential desensitization of homozygous haplotypes of the beta2-adrenergic receptor in lymphocytes.Semantic proximity Read ↗

Beta2-adrenoceptor polymorphisms: relation between in vitro and in vivo phenotypes.Semantic proximity Read ↗

[The role of beta 2-adrenoceptor gene polymorphisms in asthma].Semantic proximity Read ↗

Clinical consequences of ADRbeta2 polymorphisms.Semantic proximity Read ↗

Beta 2 Adrenergic Receptor Genetic Polymorphisms in Bronchial Asthma: Relationship to Disease Risk, Severity, and Treatment Response.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.