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Article

Reverse Genetics for Mammalian Orthoreovirus.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Stuart Johnasha D, Phillips Matthew B, Boehme Karl W

Abstract excerpt

Reverse genetics allows introduction of specific alterations into a viral genome. Studies performed with mutant viruses generated using reverse genetics approaches have contributed immeasurably to our understanding of viral replication and pathogenesis, and also have led to development of novel vaccines and virus-based vectors. Here, we describe the reverse genetics system that allows for production and recovery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28508210
DOI: 10.1007/978-1-4939-6964-7_1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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