Article
Identification of key mutations in HIV reverse transcriptase gene can influence the clinical outcome of HAART.
Journal of medical virology - 1 Jul 2001
Setti M, Bruzzone B, Ansaldi F, Borrelli P, Indiveri F, Icardi G
Abstract excerpt
Therapeutic failures due to in vivo loss of drug sensitivity are still a major problem in AIDS care. Currently, the role of and methods for detecting resistant mutant strains in patients before therapeutic choices are still under debate. To investigate the relevance of screening for key mutations alone the commercial INNO-LiPA HIV-1 RT method was applied retrospectively to analyzing several HIV codons correlated...
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