Article
Evaluation of the LiPA HIV-1 RT assay version 1: comparison of sequence and hybridization based genotyping systems.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2002
Stürmer Martin, Morgenstern Birgit, Staszewski Schlomo, Doerr Hans Wilhelm
Abstract excerpt
BACKGROUND: Specific mutations in the reverse transcriptase (RT) gene of HIV-1 are associated with reduced activity of nucleoside inhibitors used in the antiretroviral treatment of infected patients. The appearance of these mutations may result in therapy failure. Therefore, HIV-1 genotyping is a...
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