Article
[Human immunodeficiency virus and resistance].
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia - 1 Jun 1998
Coórdoba J, Otero M C, Laínez B, Pérez-Tamarit D, Molina J M, Calvo M A, Asensi F, Gobernado M
Abstract excerpt
It has been demonstrated that following prolonged treatment with reverse transcriptase inhibitors, especially with nucleoside analogs, resistant viral strains appear that show mutations in the nucleotides of the gene that codifies reverse transcriptase. These mutations cause changes in amino acid...
Topics
- Anti-HIV Agents
- Child
- Codon
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- Drug Therapy, Combination
- HIV Infections
- HIV-1
- Humans
- Mutation
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- RNA, Viral