Article
Vimentin promotes collective cell migration through collagen networks via increased matrix remodeling and spheroid fluidity
2024-06-17
Abstract excerpt
The intermediate filament (IF) protein vimentin is associated with many diseases with phenotypes of enhanced cellular migration and aggressive invasion through the extracellular matrix (ECM) of tissues, but vimentin’s role in in-vivo cell migration is still largely unclear. Vimentin is important for proper cellular adhesion and force generation, which are critical to cell migration; yet the vimentin cytoskeleton a...
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Identifiers and source
- Literature Corpus work
- bd6a1e4d-8ec1-51b5-ad45-6653cc7e780d
- DOI
- 10.1101/2024.06.17.599259